December 21, 2011 |
2011-R-0424 | |
CONNECTICUT AND MASSACHUSETTS BIOSCIENCE ASSISTANCE PROGRAMS | ||
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By: John Rappa, Chief Analyst | ||
You asked us to summarize Massachusetts' bioscience business assistance programs and compare them with Connecticut's. You also asked us to identify any major bioscience projects Massachusetts recently attracted or retained.
SUMMARY
In 2008, the Massachusetts legislature launched a 10-year, $1 billion strategy to develop and sustain the state's bioscience industry and support the academic institutions that conduct bioscience research. To implement the strategy, the legislature created many new programs and assigned them to the Massachusetts Life Science Center (MLSC), a quasi-public agency it created in 2006.
The bioscience programs provide funds and tax credits for developing infrastructure and facilities, acquiring machines and equipment, starting or expanding new businesses, and hiring college interns. They run parallel to older programs serving a wider range of businesses, including bioscience ones. Both program tracks offer the same types of assistance (e.g., loans and tax credits), but the older track is mostly for mid-stage and mature businesses while the bioscience track offers assistance for bioscience businesses at all developmental stages.
MLSC uses the bioscience programs to recruit and retain businesses. MLSC staff actively recruits bioscience businesses by attending conferences and tradeshows. The recruited businesses include branches or divisions of Biocell Center (from Italy), Integragen (from France), and Pfizer (from Groton, Connecticut), although MLSC's annual reports do not include them among the businesses that received assistance. The reports do not identify those businesses MLSC kept from leaving the state or closing.
Connecticut provides the same types of assistance to bioscience businesses as Massachusetts, but mostly through programs opened to many different types of businesses, such as manufacturers and financial service firms. The exception is the Bioscience Facilities Fund, which provides financing for constructing laboratories designed for handling chemicals, drugs, and other substances (i.e., wet laboratories). Recently, the legislature sought to stimulate and sustain the bioscience industry by funding large-scale bioscience projects at John Dempsey Hospital and the University of Connecticut Health Center.
MASSACHUSETTS BIOSCIENCE ASSISTANCE PROGRAMS
Massachusetts 2008 Life Science Initiative
In 2008, Massachusetts enacted a 10-year, $1 billion strategy to develop and sustain the state's bioscience industry, which includes biotechnology, pharmaceutical, medical devices, diagnostic, and bioinformatic businesses (2008 Mass. Chapter 130). The strategy addresses the industry's physical, human, and technological development needs and consists of many economic development programs targeting only bioscience businesses.
The $1 billion price tag includes up to $500 million in bonds for specified projects; $250 million in appropriations for research grants, fellowships, and sector-wide workforce training initiatives; and $250 million in personal and corporate business tax credits and sales tax exemptions. The tax credits are capped at $25 million per year. As Table 1 shows, the programs address the bioscience industry's long- and short-term infrastructure, workforce development, and financial needs.
Table 1: Massachusetts Life Sciences Initiatives
Physical Development | |
Long-Term Needs |
Short-Term Needs |
$500 million in bonds for specified life science infrastructure and facilities, including water purification plants and incubator buildings |
Tax Incentives ● 10%, refundable personal income and corporate tax credit against the cost of acquiring, constructing, reconstructing, or erecting real and tangible personal property used exclusively in Massachusetts ● Sales tax exemption for purchasing tangible personal property to be used for developing R&D or manufacturing facilities or utility support systems |
Human Development | |
Long-Term Needs |
Short-Term Needs |
Matching grants for: ● Supporting new personnel conducting innovative research at colleges and universities ● Attracting and retaining nationally prominent faculty ● Encouraging business-university collaborative research ● Purchasing life science demonstration and training equipment and supplies for educational laboratories and training spaces Internship Challenge Program places students and recent graduates in life science-related internship programs and reimburses businesses for up to $7,200 of the cost |
● $5,000 -$15,000 grants covering living expenses for life sciences doctoral students and post-doctoral fellows ● Grants to vocational and technical schools for purchasing or leasing equipment for training in life sciences technology and research ● 100% life science job incentive tax credit (90% refundable) for companies adding at least 50 new full-time jobs |
Technological Development | |
Long-Term Needs |
Short-Term Needs |
Regional Technology and Innovation Centers for: ● Promoting collaborative research ● Building life sciences industry data bases ● Developing life sciences workforce ● Disseminating best life sciences business practices ● Facilitating public and private investments ● Reviewing proposals for Life Sciences Center funding ● Identifying life sciences regional clusters |
Tax Incentives ● 100% personal income and corporate tax credit against Federal Food and Drug Administration user fee applications for human drugs manufactured in Massachusetts ● Nonrefundable credit applicable to R&D expenses not covered under the generic R&D credit ● Deduction for clinical expenses of testing drugs for rare diseases or conditions ● Sales tax exemption for items used in R&D ● 15-year net operating loss carried forward (normally, five-year carry forward) ● “Throwbacks” excluded from sales factor for apportioning corporate income* Financial Assistance ● Life Science Investment Fund: grants, loans, investments, and other funding to businesses, universities, institutes, and other entities for commercializing life science R&D ● Small Business Equity Investment Fund: up to $250,000 investments in early stage life sciences firms ● Small Business Matching Grant Fund: Up to $500,000 to match federal grants for commercializing production-ready new technologies ● Life Science Accelerator Program: working capital loans for early stage life science companies with less than $7.5 million in equity financing |
* “Throwback” requires companies to add sales in states where there are no corporate taxes to Massachusetts sales.
The programs are implemented by MLSC and are available to any business meeting statutory criteria that require, among other things, the business to estimate the revenue it expects to generate and the number of permanent full-time jobs it expects to create or retain. MLSC can revoke funding if the actual revenue is less than 70% of the projected revenue.
Generic Economic Development Programs
The life science programs are in addition to the Massachusetts' generic economic development programs, many of which are still available to life science businesses and predate the bioscience programs. Table 2 identifies the programs and the implementing agencies.
Table 2: Massachusetts Generic Economic Development Programs
Type of Assistance |
Massachusetts Finance and Development Authority (MassDevelopment) |
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Financing |
Financing for developing property, acquiring machinery and equipment, new and expanding technology companies, and assessing and remediating contaminated property |
No programs |
No programs |
Venture Capital |
No programs |
No programs |
Venture capital investments for start-up and expanding early-stage technology companies |
Expedited Permitting |
Helping municipalities identify appropriate priority development sites |
Funds for municipalities to identify sites for expedited permitting |
No programs |
Technical Assistance |
Helping municipalities identify and assess development feasibility of specific sites |
● Helping businesses access economic development programs ● Helping businesses obtain permits, licenses, and other regulatory approvals |
No programs |
Tax Credits |
● 10% to 40% tax credits for business projects creating jobs and generating substantial sales outside the state ● 3% investment tax credit for developing property |
No programs |
As the table shows, Massachusetts' generic programs include several that help businesses obtain necessary state and local approvals. The Massachusetts Permitting Regulatory Office helps businesses, including bioscience ones, obtain necessary licenses, permits, and approvals. It also provides grants to municipalities to identify sites where they can expeditiously approve permits for a proposed development. The office also tracks pending regulatory approvals for state funded-housing and economic development projects.
Massachusetts' generic economic development and new bioscience programs can be combined to help bioscience businesses in different developmental stages. As Table 3 shows, the generic programs focus on mid-stage or mature businesses while bioscience programs cover these and start-up and early stage businesses.
Table 3: Massachusetts Life Science Incentives Matrix
= Life Science Initiative Program | |
= Generic Economic Development Program |
Assistance Type |
Individuals and Universities |
Business Development Stages |
Infrastructure | |||
Start-ups |
Early Stage |
Mid-Stage |
Mature | |||
Grants |
New Investigator Grant |
Cooperative Research Grant |
Hiring Incentive Grant |
Infrastructure Grants | ||
New Faculty Start-up |
Internship Challenge Grants |
Infrastructure Grants | ||||
Small Business Matching Grant |
||||||
Financing |
Life Sciences Accelerator |
Emerging Technology Fund |
District Improvement Financing | |||
Export Financing |
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Tax-Exempt Industrial Bonds |
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Tax Incentives |
Refundable 10% Life Science Investment Tax Credit |
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Economic Development Incentive Program |
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3% Investment Tax Credit |
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Single Sales Tax Factor for Manufacturers |
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Sales and Use Tax Exemption |
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Refundable Life Science R&D Tax Credit |
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10% R&D Tax Credit |
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Refundable FDA User Fee Credit |
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15-year Net Operating Loss Carry Forward |
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Construction Sales Tax Exemption |
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Source: Massachusetts Biotechnology Council
Attracted or Retained Projects
MLSC and MassDevelopment report on the businesses they financed in their annual plans. MLSC identifies those it attracted to Massachusetts, but does not specifically identify those it retained there. (We assume that a retention project provides assistance to a company that might close or leave the state.) MassDevelopment does not divide projects into attraction and retention categories.
Table 4 lists the bioscience businesses that received financial assistance from MLSC and MassDevelopment and investment capital from MTDC. It also identifies projects MLSC identified as attractions projects, some of which were not listed among those that received financing or tax credits. We limited the businesses receiving tax credits to those that received over $1 million in credits. The table does not include the early-stage businesses that received MLSC assistance. Nor does it include businesses awarded tax credits by the Executive Office of Housing and Economic Development, which oversees the Massachusetts Office of Business Development, the Massachusetts Permit Regulatory Office, and several other executive branch entities.
Table 4: Bioscience Businesses Receiving MLSC and MassDevelopment Financing, 2006-2011
Company |
Amount |
Year |
Agency |
Attraction Project |
Bidex, Inc |
$2.5 million in Emerging Technology Fund loan |
2006 |
MassDevelopment |
Not indicated |
Biocell Center |
No assistance reported |
2009 |
MLSC |
Yes—from Italy |
Biogen Idec MA, Inc. |
$1.5 million in tax credits |
2010 |
MLSC |
No |
Blue Sky Biotech, Inc. |
$175,000 Emerging Technology Fund loan |
2008 |
MassDevelopment |
Not indicated |
$150,000 Emerging Technology Fund loan |
2006 |
MassDevelopment |
Not indicated | |
$150,000 equipment loan |
2007 |
MassDevelopment |
Not indicated | |
Bristol-Myer Squibb |
$112 million mortgage guarantee |
2009 |
MassDevelopment |
Not indicated |
Cubist Pharmaceuticals, Inc |
$1.7 million in tax credits |
2010 |
MLSC |
No |
CYTOO |
No assistance reported |
2009 |
MLSC |
Yes—from France |
Early Sense |
No assistance reported |
2011 |
MLSC |
Yes—from Israel |
ECI Biotech |
$400,000 in Emerging Technology Fund loan |
2008 |
MassDevelopment |
Not indicated |
Evaluate Pharma |
No assistance reported |
2011 |
MLSC |
No |
Genzyme Corporation |
$6.0 million in tax credits |
2010 |
MLSC |
No |
Hyaluron Corporation |
$1 million Emerging Technology Fund loan |
2006 |
MassDevelopment |
Not indicated |
$500,000 export loan guarantee |
2006 |
MassDevelopment |
Not indicated | |
Image Diagnostic |
$1.5 million in tax-exempt bond financing |
2009 |
MassDevelopment |
Not indicated |
Integragen |
No assistance reported |
2011 |
MLSC |
Yes—France |
Marine Biological Laboratories |
$3.4 million in tax-exempt bond financing |
2006 |
MassDevelopment |
Not indicated |
Massachusetts Biomedical Initiative |
$1 million in Emerging Technology Fund loan |
2006 |
MassDevelopment |
Not indicated |
$1 million real estate loan |
2006 |
Mass Development |
Not indicated | |
Masy System, Inc. |
● $490,000 export loan ● $700,000 equipment loan |
2011 |
MassDevelopment |
Not indicated |
Merrimack Pharmaceuticals |
$1.5 million in tax credits |
2010 |
MLSC |
No |
$1.3 million in tax credits |
2011 |
MLSC |
No | |
Millstone Medical Outsourcing |
$4.5 million in tax-exempt bond financing |
2009 |
MassDevelopment |
Not indicated |
Neostem, Inc. |
No assistance reported |
2010 |
MLSC |
Yes—International, multiple locations |
NX Stage Medical, Inc. |
$1.3 million in tax credits |
2011 |
MLSC |
No |
Pfizer Center for Therapeutic Innovation |
No assistance reported |
2011 |
MLSC |
Yes—Groton, Connecticut |
Pharmalucence, Inc. |
$20 million in Recovery Zone Bond financing |
2010 |
MassDevelopment |
Not indicated |
Qteros |
$2 million Emerging Technology Fund loan |
2010 |
MassDevelopment |
Not indicated |
Sagentia |
No assistance reported |
2011 |
MLSC |
Yes—United Kingdom |
Shire Human Genetic Therapies, Inc. |
$6.3 million in tax credits |
2010 |
MLSC |
No |
$5.8 million in tax credits |
2011 |
MLSC |
No | |
Sanofi-Aventis, U.S., Inc. |
$2.5 million in tax credits |
2011 |
MLSC |
Yes—from France |
Systagenix |
No assistance reported |
2009 |
MLSC |
Yes—from United Kingdom |
Thomophase Corporation |
Venture capital investment, amount unspecified |
2011 |
MTDC |
Not indicated |
Vertex Pharmaceuticals |
$2.2 million in tax credits |
2011 |
MLSC |
No |
Sources: MLSC FY 2010 and 2011 annual reports and MassDevelopment annual reports 2006-2010, and MTDC website.
CONNECTICUT'S ECONOMIC ASSISTANCE FOR BIOSCIENCE BUSINESSES
Connecticut provides the same kind of economic assistance to bioscience businesses as Massachusetts, but does so through agencies and programs serving several different industry sectors.
● The Department of Economic and Community Development, like Massachusetts' Executive Office of Housing and Economic Development, finances business and municipal development projects and helps expedite state approvals of large-scale economic development projects.
● The Connecticut Development Authority, like MassDevelopment, provides loans, loan guarantees, and tax-exempt bond financing for business development projects. It also provides sales and use tax exemptions for these projects.
● Connecticut Innovations, Inc.(CII), like MTDC, mostly invests in technology businesses, but also finances the construction of wet laboratories and related facilities (Bioscience Facilities Fund) and provides tax credits to individuals investing in small businesses developing new technologies (Angel Investor Tax Credit Program).
The legislature recently shifted gears, authorizing bonds for large-scale bioscience projects as a way to stimulate and develop the bioscience industry. PA 10-104 provided over $360 million in bonds and other funds for constructing a new bed tower; renovating academic, clinical, and research space at John Dempsey Hospital; and developing regional health network initiatives. It also extended enterprise zone property tax exemptions and corporation business tax credits to bioscience businesses in Hartford and designated sections of Farmington, New Britain, and Bristol. (PA 11-140 extended these benefits to designated sections of Plainville.)
PA 11-2, October Special Session, authorized CII to develop a bioscience industry cluster centered on a new Jackson Labs research facility to be constructed at the University of Connecticut Health Center. It authorized up to $290 million in bonds over 10 years for the laboratory's construction, operation, and research activities.
LINKS
2008 Mass. Chapter 130, http://www.malegislature.gov/Laws/SessionLaws/Acts/2008/Chapter130
Massachusetts Life Science Center, http://www.masslifesciences.com/mission.html
Massachusetts Biotechnology Council, “Massachusetts Life Science Incentive Matrix,” http://www.massbio.org/writable/editor_files/2010_incentives.pdf
MassDevelopment, http://www.massdevelopment.com/
Massachusetts Executive Office of Housing and Economic Development, http://www.mass.gov/hed/
Massachusetts Economic Development Incentive Program, http://www.mass.gov/hed/business/incentives/edip/edip-program-information.html
Massachusetts Investment Tax Credit, http://www.mass.gov/hed/business/incentives/investment-tax-credit.html
Massachusetts Technology Development Corporation, http://www.mtdc.com/
Massachusetts Permit Regulatory Office, http://www.mass.gov/hed/economic/eohed/pro/about/mission-of-the-office.html
Connecticut Department of Economic and Community Development, http://www.ct.gov/ecd/site/default.asp
Connecticut Development Authority, http://www.ctcda.com/
Connecticut Innovations, Inc., http://www.ctinnovations.com/FundingOpportunities.aspx
Connecticut Innovations, Inc., Bioscience Facilities Fund, http://www.ctinnovations.com/FundingOpportunities/BioScienceFacilitiesFund.aspx
Connecticut Innovations, Inc., Angel Investor Tax Credit, http://www.ctangeltaxcredit.com/
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